The Advanced Quality One Step Malaria (Pf) Test is a colloidal gold-enhanced, rapid immunochromatographic assay for testing, in vitro, the presence of plasmodium falciparum malaria in blood. The test is an antigen-capture assay detecting the presence of a specific soluble protein, histidine-rich protein II (Pf HRP-II), which is present in, and released from infected red blood cells. The assay is intended for use with whole blood and does not require additional instruments.