The Maverick Diagnostic System (MDS) uses silicon chip-based photonic ring resonator technology to perform multiple simultaneous rapid tests on a small volume of whole blood or serum. The MDS detects changes in resonance wavelength as macromolecules, such as autoantibodies, bind to their respective antigens that are bound to the chip; eliminating the need for fluorescent, luminescent, or radioactive labels used in other immunoassay formats. The system is cloud-connected for assay protocol retrieval and clinical oversight.